Pharma / CDMO / Clinical
Homogeneous conjugates for therapeutics and diagnostics
Homogeneous conjugates for therapeutics and diagnostics
In therapeutic development, precise control of conjugate composition matters for product characterization, consistency and manufacturing reproducibility. Connectase enables site-specific protein modification through an enzymatic reaction that forms a stable covalent bond. This offers a promising approach for ADCs and other protein-based therapeutics where defined conjugation is important. We work with pharmaceutical developers and CDMOs to assess performance on relevant constructs, establish feasibility and adapt the process to specific development requirements. We are positioning Connectase in therapeutic development and manufacturing. We aim to work closely with partners to generate proof of concept, deliver the required quality and regulatory fit and build a pipeline of superior targeted therapeutics based on proprietary conjugation technology.